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01/03/2012
Vinco's Smart PS - The Smart Choice Vinco's Smart PS finished dosage softgels feature an exclusive fluid dispersion phosphatidylserine material that has significantly enhanced stability for maximum brain benefits. Research in animals and humans has shown.....
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01/02/2012
Happy New Year! We, here at Vinco, would like to start off the New Year on the right foot by thanking you for your continued support.
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Melatonin 10mg
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Item # V-MEL10
60 capsules per bottle
Natural Source
A powerful antioxidant.
Shown to help adjust circadian rhythms for healthier sleep cycles.
PROFESSIONAL FORMULATION
Readjusting Our Body's Circadian Mechanism
If we were to live our lives in buildings of artificial light, ones with no connection to environmental patterns of night and day,our bodies will develop what appears to be normal cycles of wakefulness and sleep. These cycles, occurring at approximate25 hr. intervals, have been given the term Circadian Rhythms from the latin Circa Diem, meaning about a day. Take a trip across a few time zones, or begin working the night shift and your body's circadian rhythm will introduce itself.' Elements of daily behavior such as lunchtime, or bedtime as well as person's level of alertness for various tasks will seem strange and awkward to perform. Studies suggest that this occurs due to the fact that the body's circadian "clock" is not synchronized with its new environments patterns of night and day. Eventually these patterns do reach in and allow the brain to respond in accordance to the outside world; but this takes time. To be effective in combating disorders linked to circadian disfunction, including jet lag, seasonal affective disorder, (due to decreases in the amount of sunlight during the winter months) and sleep disorders such as Phase Delay Sleep Syndrome and insomnia, this internal rate of adjustment can be sped up. The hormone Melatonin, 5-methoxy-n-acetyl tryptomine, is secreted by the brain's pineal gland, (but only at night,) and has been called the chemical expression of darkness. Lengthen the night, and melatonin is produced for a longer period. Lengthen the period of light, and diminish the amount of Melatonin production; the level of the hormone presumably tells the body when it's night time. This internal rhythm is "entrained" to its owner's surroundings by the environmental stimulus of light and dark patterns. We receive this information from the eyes, via the optic nerves. As the sun is going down at the end of a normal day, there is less registered light passing through the optic nerves to the brain. As we continue towards darkness, two small clusters of cells called the Suprachiasmatic Nuclei (SCN), located in the Hypothalamus, recognize this transition and trigger the pineal gland to start producing melatonin. Each morning, the reverse takes place. When light is once again detected, the SCN sends the signal to "Turn Off" the pineal gland, and a wake-up message is sent to the brain. There is evidence that melatonin can produce significant phase advances when administered in the late afternoon and early evening, at doses that will be largely eliminated prior to the subsequent sleep period. This suggests that the improvement in sleep following evening administration is more likely to be related to circadian effects.
Dr. Richard J. Wurtman, professor of Neuroscience at the Massachusetts Institute of Technology reports that studies show Melatonin, whether secreted by the pineal gland in the brain or given as supplements in small doses, function naturally as a sleep inducing hormone. Exogeneously administered Melatonin can entrain circadian rhythms and can change the phase of the endogenous Melatonin rhythms, alleviate the symptoms of Jet Lag, and facilitate re-entrainment of these clock oriented rhythms. Thus melatonin, administered in lower doses, may modulate the entrainment process in humans and be useful in treating circadian rhythm disorders.
Dr. Judith Vaitukaitis, Director of the National Center for Research Resources said the M.I.T. findings offer hope, "For a Natural non-addictive agent that could improve sleep for millions of Americans."
Disorders and Complications receiving benefit from Melatonin supplementation:
Insomnia
Jet Lag
Phase Delay Sleep Syndrome
Seasonal Affective Disorder
Alzheimer's Disease
Multiple Sclerosis
Parkinson's Disease
Neurotoxic damage
Retrolenticular fibroplasia
Photic retinopathy
Ocular hemorrhage
Hypertensive cardiovascular injury
Degenerative retinal damage
Studies and Research Findings:
20 volunteers with experience in transcontinental flying were pretreated with Melatonin for three days before the flight, during the flight, and once daily for three days following arrival at their destination. Compared to placebo groups, the treated subjects reported significantly fewer feelings of jet lag and took less time to establish a normal sleep pattern. They also reached "normal" energy levels earlier than did the placebo group, and reported significantly lower levels of tiredness during the day. (Petrie, 1989)
Melatonin was administered to transmerridian travelers. 17 subjects were treated over a period of 14 days following a flight from London to San Fransisco. Compared with placebos, Melatonin significantly reduced the negative feelings of jet lag and increased subjective alertness. Those subjects who received melatonin also reported reduced sleep onset latencies and improved sleep quality. In addition, endogenous Melatonin rhythms resynchronixed more rapidly than for those who were receiving placebos. (Arendt, 1987)
Melatonin was administered to a blind subject who did not have a regular sleep-wake pattern and was phase delaying by approximately one hr per day. After administering Melatonin at 5:00 pm for a six week period, it was reported that there was a significant improvement in the sleep-wake cycle. (Arendt, 1988)
A severely retarded blind 9 year old, with a free running sleep-wake period was given Melatonin at 6:00 pm. This induced a regular 24 hr sleep- wake pattern and was associated with a corresponding change in the period of the endogenous Melatonin and cortisol rhythms. After five months of treatment, when a placebo was substituted, the child's sleep pattern deteriorated to previous levels and the circadian system reverted to a period greater than 24 hrs. It was assumed that, in the patient, melatonin improved sleep-wake behavior via indirect action on the circadian system. (Palm, 1991)
What our product is not...
Not a synthetic: Vinco's Melatonin is not the creation of some chemical lab. There's no chance of the disruption in body chemistry that is often linked to the synthetic forms, (because of not being recognized as part of the biochemical machinery of the body; which can lead to possible side effects.) Vinco's Melatonin has been designed to be recognized as part of the natural framework of the body. Not a bovine powder: While ground-up pineal products may offer support for glandular tissue, they do not contain the specific, individualized constituents of that gland, and should not be confused with melatonin itself or its effects. Why? Consider this. The pineal gland, unlike other glands, does not have a "storage compartment" where excess melatonin can be found in abundant proportions. The gland is a factory, not a warehouse. While this ground-up gland may be able to aid the factory, don't expect it to contain the final products. Could we guess a time when, upon extraction of the pineal gland, we could expect to find melatonin? Maybe. Maybe if we could take out the factory while it's "turned on." But this factory operates at night, and seeing how these glandulars are bovine in nature, or in other words a byproduct of the cattle/meat industries, we can understand how unlikely it would be to find worthy levels of melatonin. How many cattle are slaughtered at night?
What our product is...
An organic product born from a manufacturing concept which can guarantee the content of your supplement. Its a process called Fermentation/Extraction. Similar to the production of wine where natural ingredients are introduced to one another, allowed the time to properly ferment, and then harvested with care, we use a pure vegetable source to deliver a superior melatonin. No synthetics, no cheap gimmicks, just an efficacious product manufactured under the finest quality standards.
Directions for Use:
As a dietary supplement for adults and children 12 or more years of age, take one capsule or tablet one time daily, or as directed by a qualified healthcare professional.
References:
1. Dawson, D., & Encel, N., "Melatonin and Sleep in Humans," J Pineal Res., 15:1-12, 1993
2. "Light Sleepers," The Economist, 323:(7754), 85, 1992
3. Nadis, S., "Cure for the Winter Blues," Tech Rev., 90:8, 12, 1987
4. Repport, S., et al., "Putative Melatonin Receptors in a Human Biological Clock," Science, 242:4875, 78, 1988
5. Weiss, R., "Recent awakenings in Melatonin Research," Science News, 136:20, 317, 1989
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